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Nitrile gloves are preferred for handling hazardous materials due to their excellent chemical resistance and durability. Unlike latex gloves, nitrile gloves do not cause allergic reactions in some individuals, making them a safer option for use in environments where hazardous materials are present.

Nitrile is also puncture-resistant, providing a better barrier protection against sharp objects or chemicals compared to other glove types like vinyl or cotton. While latex gloves offer a good fit and dexterity, they lack the chemical resistance needed for hazardous materials handling and pose a risk of allergy. Cotton gloves offer no chemical protection and are mainly used for light handling or situations where the risk of exposure to hazardous materials is minimal. Vinyl gloves provide a less effective barrier than nitrile and are generally not suitable for heavy-duty tasks involving hazardous substances. Hence, nitrile gloves emerge as the optimal choice for safety and protection in these scenarios.